March 25, 2023 7:17 am

The authors wrote that they think that their findings could have prospective clinical and public well being implications and highlight the higher part of metabolic well being status than obesity in IOP elevation. (Adobe Stock image)

South Korean researchers reported that people who have been metabolically unhealthy with a typical weight had larger intraocular pressures (IOPs) compared with these who have been metabolically healthful regardless of the physique mass index (BMI).1

The investigators are from the Division of Ophthalmology, Yeouido St. Mary’s Hospital, College of Medicine, and the Overall health Promotion Center, Seoul St. Mary’s Hospital, College of Medicine, both from the Catholic University of Korea, Seoul.

When obesity has been connected with enhanced IOPs, the final results to now have been inconclusive. The analysis group, led by Younhea Jung, MD, investigated the IOP amongst groups with diverse combinations of obesity status and metabolic well being status.

The study incorporated 20,385 adults (age variety, 19 to 85 years) involving Could 2015 and April 2016. The individuals have been divided into 4 groups according to obesity (BMI ≥ 25 kg/m2) and the metabolic well being status that was defined primarily based on health-related history or abdominal obesity, dyslipidemia, low higher-density lipoprotein cholesterol, higher blood stress, or higher fasting blood glucose levels.

The authors reported that the imply IOP of the metabolically unhealthy obese group (14.38 ± .06 mm Hg) was the highest, followed by that of the metabolically unhealthy typical-weight group (14.22 ± .08 mm Hg), and the metabolically healthful groups (p &lt .001 13.50 ± .05 mm Hg and 13.06 ± .03 mm Hg in the metabolically healthful obese and metabolically healthful typical-weight groups, respectively).

“Subjects who have been metabolically unhealthy had larger IOPs compared to their counterparts who have been metabolically healthful at all BMI levels, and there was a linear raise in IOP as the quantity of metabolic illness elements enhanced, but no distinction involving typical-weight vs. obese people,” the authors wrote. “While obesity, metabolic well being status, and each and every element of metabolic illness have been connected with larger IOP, these in the metabolically unhealthy typical-weight group showed larger IOPs than these who have been metabolically healthful but obese, which indicates that the metabolic status has a higher effect than obesity on IOP.

The authors wrote that they think that their findings “have prospective clinical and public well being implications and highlight the higher part of metabolic well being status than obesity in IOP elevation.”

Reference

1. Jung Y, Kim GN, Oh EB, et al. Metabolic well being, obesity, and intraocular stress. J Clin Med. 202312:2066 https://doi.org/ten.3390/jcm12052066

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