NASA Spaceline Present Awareness List #1,051 26 Could 2023 (Space Life Science Analysis Benefits)

Space Biology on ISS

NASA

SPACELINE Present Awareness Lists are distributed by way of listserv and are obtainable on the NASA Activity Book web page at https://taskbook.nasaprs.com/Publication/spaceline.cfm. 

Please send any correspondence to Shawna Byrd, SPACELINE Present Awareness Senior Editor, [email protected].

Contact for articles to cite in the weekly lists: Authors at NASA Centers and NASA PIs—do you have an post that has not too long ago published or will publish in the upcoming weeks inside a peer-reviewed journal and is in the scope of space life sciences? If so, send it our way! Send your post to the e mail address described above. Articles received by Wednesday will seem inside that week’s list—articles received following Wednesday will seem the following week.

Papers deriving from NASA help:

1

Faerman A, Clark JB, Sutton JP.

Neuropsychological considerations for lengthy-duration deep spaceflight.

Front Physiol. 2023 Could 1914:1146096. Evaluation.

https://doi.org/ten.3389/fphys.2023.1146096

Note: This post is aspect of Analysis Subject “Brains in Space: Effects of Spaceflight on the Human Brain and Behavior-Volume II” (https://www.frontiersin.org/analysis-subjects/47491/brains-in-space-effects-of-spaceflight-on-the-human-brain-and-behavior—volume-ii#overview). The Analysis Subject also involves articles from prior Present Awareness Lists #1,041 https://doi.org/ten.3389/fphys.2023.1141078 and #1,046 https://doi.org/ten.3389/fncir.2023.1135434. This post may perhaps be obtained on the web with out charge.

Journal Effect Issue: 3.342

Funding: “Support from the Translational Analysis Institute for Space Well being via NASA Cooperative Agreement NNX16AO69A is gratefully acknowledged. JS is supported by the Friedkin Chair for Analysis in Sensory Technique Integration and Space Medicine at Baylor College of Medicine.”

two

Shelhamer M, Antonsen E, Reynolds R.

The will need for a systems strategy in spaceflight wellness and medicine.

2023 IEEE Aerospace Conference. 2023 Could 15.

https://doi.org/ten.1109/aero55745.2023.10115773

PI: M. Shelhamer

Note: This post is a conference proceeding published by a peer-reviewed journal.

Journal Effect Issue: 0.88

Funding: “MS is supported by NASA 80NSSC19K0487.”

three

Shelhamer M, Gersh JR.

A mission architecture to integrate human and spacecraft functional functionality.

2023 IEEE Aerospace Conference. 2023 Could 15:1-eight.

https://doi.org/ten.1109/aero55745.2023.10115715

PI: M. Shelhamer

Note: This post is a conference proceeding published by a peer-reviewed journal.

Journal Effect Issue: 0.88

Funding: “MS is supported by NASA 80NSSC19K0487.”

four

Hilditch CJ, Pradhan S, Costedoat G, Bathurst NG, Glaros Z, Gregory KB, Shattuck NL, Flynn-Evans EE.

Sex variations in perceptions of sleep inertia following nighttime awakenings.

Sleep Adv. 20234(1):zpac043.

https://pubmed.ncbi.nlm.nih.gov/37193286

Note: This post may perhaps be obtained on the web with out charge.

Journal Effect Issue: Not obtainable for this journal

Funding: “This operate was supported in aspect by the Naval Healthcare Analysis Center’s Naval Sophisticated Healthcare Improvement Plan (MIPR N3239820WXHN007) and the National Aeronautics and Space Administration Airspace Operations and Security Plan, Technique Wide Security.”

five

Saint-Guillain M, Vanderdonckt J, Burny N, Pletser V, Vaquero T, Chien S, Karl A, Marquez J, Wain C, Comein A, Casla IS, Jacobs J, Meert J, Chamart C, Drouet S, Manon J.

Enabling astronaut self-scheduling employing a robust sophisticated modeling and scheduling program: An assessment throughout a Mars analogue mission.

Adv Space Res. 2023 Apr five. On the internet ahead of print.

https://doi.org/ten.1016/j.asr.2023.03.045

Note: From the abstract: “Human lengthy duration exploration missions (LDEMs) raise a quantity of technological challenges. This paper addresses the query of the crew autonomy: as the distances improve, the communication delays and constraints have a tendency to avoid the astronauts from getting monitored and supported by a genuine time ground handle.”

Journal Effect Issue: 2.611

Funding: T. Vaquero and S. Chien are affiliated with NASA Jet Propulsion Laboratory. J. Marquez is affiliated with NASA Ames Analysis Center.

six

Schroeck H, Whitty MA, Martinez-Camblor P, Voicu S, Burian BK, Taenzer AH.

Anaesthesia clinicians’ perception of security, workload, anxiousness, and strain in a remote hybrid suite compared with the operating area.

Br J Anaesth. 2023 Could 16S0007-0912(23)00203-9. On the internet ahead of print.

https://pubmed.ncbi.nlm.nih.gov/37202262

Journal Effect Issue: 11.719

Funding: B.K. Burian is affiliated with NASA Ames Analysis Center.

7

Li M, Lee JD.

Modeling target alignment in human-AI teaming: A dynamic game theory strategy.

Proc Hum Elements Ergon Soc Annu Meet. 2022 Oct66(1):1538-42.

https://doi.org/ten.1177/1071181322661047

PI: J.D. Lee

Note: This post is a meeting proceedings that published in peer-reviewed Sage journals. This post may perhaps be obtained on the web with out charge.

Journal Effect Issue: 3.598

Funding: “This operate was supported by NASA Human Analysis Plan No. 80NSSC19K0654.”

eight

Buettmann EG, Chlebek C, Lockard CA, Clayton SW, Lewis KJ, Collins KH.

Post or perish? Social media methods for disseminating orthopedic analysis.

J Orthop Res. 2023 Could ten. On the internet ahead of print.

https://doi.org/ten.1002/jor.25588

PI: E.G. Buettmann

Note: This post may perhaps be obtained on the web with out charge.

Journal Effect Issue: 3.103

Funding: “Dr. Evan Buettmann was supported by the Translational Analysis Institute for Space Well being (TRISH) via Cooperative Agreement with NASA (NNX16AO69A). Dr. Kelsey Collins was supported by NIAMS (Grant K99AR078949).”

_______________________________________________________

Other papers of interest:

1

Almosa AS, Lockwood MB, Green SJ.

Effects of spaceflight on the human gastrointestinal tract microbiome.

J Indian Inst Sci. 2023 Could 23. Evaluation.

https://doi.org/ten.1007/s41745-023-00384-7

Note: From the abstract: “In this brief assessment, we summarize the present state of know-how on the impact of space travel on the human gut microbiome, which includes analysis styles that involve animals (rodents), humans, and novel simulations. Experiments have been carried out beneath circumstances of spaceflight, ground-primarily based, and analogous flight simulation.”

two

Ejova A, Searston RA, Stephens R, Semmler C.

Clear considering in deep space: A guide by cognitive scientists.

In: de Zwart M, Henderson S, Culton J, Turnbull D, Srivastava A, eds. Human Makes use of of Outer Space: Return to the Moon. Singapore: Springer Nature Singapore, 2023. p. 31-47.

https://doi.org/ten.1007/978-981-19-9462-three_three

three

Oxlad M, Whitburn S, Carter AJ.

Optimizing mission results: A holistic strategy to picking the greatest men and women to travel to space.

In: de Zwart M, Henderson S, Culton J, Turnbull D, Srivastava A, eds. Human Makes use of of Outer Space: Return to the Moon. Singapore: Springer Nature Singapore, 2023. p. five-29.

https://doi.org/ten.1007/978-981-19-9462-three_two

four

Sakaki T, Koizumi T, Ikeido Y, Soga K, Wakabayashi K, Hoson T.

Improve in steryl glycoside levels and stimulation of lipid raft formation in azuki bean epicotyls beneath hypergravity circumstances.

Life Sci Space Res. 2023 Aug 2338:53-eight.

https://doi.org/ten.1016/j.lssr.2023.05.005

Note: A centrifuge was utilized in this study.

five

Lv W, Peng X, Tu Y, Shi Y, Song G, Luo Q.

YAP [Yes-associated protein] inhibition alleviates simulated microgravity-induced mesenchymal stem cell senescence by way of targeting mitochondrial dysfunction.

Antioxidants. 2023 Apr 2312(five):990.

https://doi.org/ten.3390/antiox12050990

Note: A 2D clinostat was utilized in this study. From the abstract: “Weightlessness in space leads to bone loss, muscle atrophy, and impaired immune defense in astronauts. Mesenchymal stem cells (MSCs) play important roles in sustaining the homeostasis and function of the tissue. On the other hand, how microgravity impacts the qualities MSCs and the associated roles in the pathophysiological modifications in astronauts stay barely identified.” This post is aspect of Subject “Advances in Astrobiology” (https://www.mdpi.com/subjects/T9B7L6S956). This post may perhaps be obtained on the web with out charge.

six

Shamei A, Sóskuthy M, Stavness I, Gick B.

Postural adaptation to microgravity underlies fine motor impairment in astronauts’ speech.

Sci Rep. 2023 Could 2213:8231.

https://pubmed.ncbi.nlm.nih.gov/37217497

Note: From the post: “The authors declare that the information utilized inside this evaluation was obtained from publicly obtainable sources, and all analysis was completed in accordance with human analysis ethics suggestions and regulations. The National Aeronautics and Space Administration (NASA) delivers audio and video for a choice of missions via the public NASA photos archive, which consists of audio and video files of Astronaut interviews for chosen missions. Audio files from each and every mission have been chosen mainly because they function substantial speech information (involving 70 and 120 s of speech) of astronauts right away ahead of and following their respective missions, permitting direct comparisons of vowel space ahead of and following adaptations to microgravity. We evaluated vowel formants from 4 astronauts across 4 STS missions: (i) STS-129 (ii) STS-133, (iii) STS-134, and (iv) STS-135.” This post may perhaps be obtained on the web with out charge.

7

Yue Y, Yang J-Q, Lu S-Y, Ge J, Nie H-Y, Liu K-G, Liu F, Li H, Yan H-F, Zhang T, Sun P-M, Sun H-W, Yang J-W, Zhou J-L, Cui Y.

Simulated microgravity altered the proliferation, apoptosis, and extracellular matrix formation of L929 fibroblasts and the transforming development aspect-β1/Smad3 signaling pathway.

Skin Res Technol. 2023 Could 829(five):e13341. On the internet ahead of print.

https://doi.org/ten.1111/srt.13341

Note: A rotary cell culture program was utilized in this study. This post may perhaps be obtained on the web with out charge.

eight

Zhang Y, Huang H, Yao C, Sun X, He Q, Choudharyc MI, Chen S, Liu X, Jiang N.

Fresh Gastrodia elata blume alleviates simulated weightlessness-induced cognitive impairment by regulating inflammatory and apoptosis-associated pathways.

Front Pharmacol. 2023 Could 314:1173920.

https://pubmed.ncbi.nlm.nih.gov/37205911

Note: Hindlimb unloading study. This post is aspect of Analysis Subject “Exploring the Crucial Targets and Compounds That Manipulate Brain Neurocircuits Against Mental Problems and Psychiatric” (https://www.frontiersin.org/analysis-subjects/44928/exploring-the-essential-targets-and-compounds-that-manipulate-brain-neurocircuits-against-mental-issues-and-psychiatric#overview). The Analysis Subject also involves an post from prior Present Awareness List #1,050 https://doi.org/ten.3389/fphar.2023.1167398. Further articles will be forthcoming and may perhaps be discovered in the hyperlink to the Analysis Subject. This post may perhaps be obtained on the web with out charge.

9

Sim HJ, So HS, Poudel SB, Bhattarai G, Cho ES, Lee JC, Kook SH.

Osteoblastic Wls ablation protects mice from total physique irradiation-induced impairments in hematopoiesis and bone marrow microenvironment.

Aging Dis. 2023 Jun 114(three):919-36.

https://pubmed.ncbi.nlm.nih.gov/37191410

Note: This post may perhaps be obtained on the web with out charge.

ten

Zhang Q, Gerweck LE, Cascio E, Gu L, Yang Q, Dong X, Huang P, Bertolet A, Nesteruk KP, Sung W, McNamara AL, Schuemann J.

Absence of tissue-sparing effects in partial proton FLASH irradiation in murine intestine.

Cancers (Basel). 2023 Apr 1315(eight):2269.

https://pubmed.ncbi.nlm.nih.gov/37190197

Note: This post may perhaps be obtained on the web with out charge.

11

Waldbaum JDH, Xhumari J, Akinsuyi OS, Arjmandi B, Anton S, Roesch LFW.

Association involving dysbiosis in the gut microbiota of main osteoporosis sufferers and bone loss.

Aging Dis. 2023 Apr 28. Evaluation.

https://pubmed.ncbi.nlm.nih.gov/37199579

Note: This post may perhaps be obtained on the web with out charge.

12

Badakva AM, Miller NV, Zobova LN.

Integration of vestibular, visual, and proprioceptive inputs in the cerebral cortex throughout movement handle.

Hum Physiol. 2023 Apr 2749(two):176-82. Evaluation.

https://doi.org/ten.1134/S0362119722600515

13

Kelly KR, Palombo LJ, Jensen AE, Bernards JR.

Efficacy of closed cell wet-suit at numerous depths and gas mixtures for thermoprotection throughout military coaching dives.

Front Physiol. 2023 Could 2414:1165196.

https://doi.org/ten.3389/fphys.2023.1165196

Note: This post may perhaps be obtained on the web with out charge.