- Evaxion created a genetic adjuvant technologies that boosts the immune responses of viral, bacterial and cancer vaccines
- Preclinically validated for each DNA and mRNA vaccines, and prepared for clinical testing
- Anticipated significant industry prospective for DNA and mRNA vaccines against cancer, viral and bacterial illnesses
COPENHAGEN, Denmark, Could 25, 2023 (GLOBE NEWSWIRE) — Evaxion Biotech A/S (NASDAQ: EVAX) (“Evaxion” or the “Company”), a clinical-stage biotechnology organization specializing in the discovery and improvement of AI-powered immunotherapies, nowadays unveils the technologies behind its novel, proprietary genetic adjuvant created to improve the effectiveness of DNA and mRNA vaccines for infectious illnesses and cancer.
Most up-to-date information from the adjuvant system had been presented at Evaxion’s reside stream R&D Day, Could 25, 2023.
“We are excited to present this novel genetic adjuvant technologies to the worldwide scientific neighborhood. It boosts Evaxion´s personal DNA technologies and has the prospective to increase the impact of practically any vaccine. We foresee a terrific industry prospective in that this technologies seems to be very powerful in each DNA and mRNA primarily based vaccines against cancer as nicely as infectious illnesses,” stated Per Norlén, CEO at Evaxion.
Evaxion´s novel genetic adjuvant carries the code for CCL19, a molecule recognized to attract immune cells, notably antigen presenting cells, and can be encoded into either DNA or mRNA vaccines with the aim of boosting the immune response.
Most up-to-date information show that the genetic adjuvant technologies boosts the antitumor impact in preclinical tumor models, and induces neutralizing antibodies and T-cell responses against each viral and bacterial antigens:
Per Norlén continues, “By encoding the immune-stimulating molecule CCL19 into either DNA or mRNA vaccines, we have demonstrated considerable enhancement of the vaccines effectiveness. We think that this advancement holds immense prospective for vaccine improvement, as it boosts each B cell and T cell immune responses, producing it applicable to a wide variety of vaccines. Constructing on the encouraging preclinical final results, the subsequent step is to validate the technologies in sufferers.”
Evaxion aims to bring the genetic adjuvant technologies into clinical trials later this year as component of the customized cancer immunotherapy system EVX-03.
Please go to the Investors section of Evaxion’s web page to access a replay of the R&D Day presentations.
About Evaxion
Evaxion Biotech A/S is a pioneering organization creating AI-powered immunotherapies. Evaxion’s proprietary and scalable AI technologies decode the human immune program to find out and create novel immunotherapies for cancer, bacterial illnesses, and viral infections. Evaxion has a broad pipeline of candidates, which includes 3 customized cancer immunotherapies. It is situated in Hørsholm, Denmark, with 50 workers listed on the Nasdaq New York stock exchange. For additional details, please go to www.evaxion-biotech.com.
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